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When switching from therapies with immune effects, take into account the duration and mechanism of action of these therapies when initiating Ergomar (Ergotamine Tartrate Tablets)- Multum SC.

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The dose of sensitive CYP3A substrates with a narrow therapeutic index may need to be reduced if coadministered with palbociclibtacrolimus will increase the level or effect of paliperidone by P-glycoprotein (MDR1) efflux transporter.

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